PhD researcher - genetic modifiers in rare kidney disease32 - 36 hoursResearch universityResearch & EducationNew

All vacancies PhD researcher - genetic modifiers in rare kidney disease Apply All vacancies New PhD researcher - genetic modifiers in rare kidney disease Start your PhD in an international research project at the interface of genetics, clinical medicine and fundamental research. Closing date 01-09-2026 3794 32 - 36 hours Research university Research & Education Apply Closing date 01-09-2026 3794

As a PhD candidate/physician-scientist, you will investigate the genetic factors that explain why one patient with hereditary cystic kidney disease develops kidney failure at a young age, while a sibling carrying the same disease-causing mutation maintains stable kidney function well into later life. Your research will contribute to the development of personalized prediction and treatment strategies for hereditary kidney diseases. Read more about the project on Amazing Erasmus MC . You will contribute to a unique international research project combining genomics, bioinformatics, and advanced laboratory techniques. You will work with an international cohort of sibling pairs with highly discordant disease trajectories. Using whole-genome sequencing, you will identify genetic variants that influence disease progression. These findings will subsequently be validated in two independent patient cohorts and functionally investigated using patient-derived kidney organoids (mini-kidneys). Your work will include the collection and analysis of clinical and genetic data, performing bioinformatics analyses, designing and conducting laboratory experiments, and presenting research findings. You will work closely with nephrologists, clinical geneticists, biologists, pathologists, and other physician-scientists and researchers within a European consortium. During your PhD, you will receive intensive supervision from Dr Mahdi Salih and Prof. Ewout Hoorn . There will be ample opportunities to attend courses, participate in international conferences, and collaborate with leading research groups. You will develop into an independent researcher with expertise in genetics, bioinformatics, and experimental research. You will publish in international scientific journals and build a strong international research network, providing an excellent foundation for a career in academic medicine or biomedical research. Work environment Work environment You will join the Rotterdam Kidney Lab , part of the Department of Nephrology and Kidney Transplantation within the Department of Internal Medicine at Erasmus MC. Our research focuses on fluid and electrolyte disorders, chronic kidney disease, hypertension, and hereditary kidney diseases such as ADPKD. We combine fundamental and clinical research in a highly translational environment, bringing discoveries from the laboratory to the patient and back again. You will become part of a diverse and ambitious team of clinicians, professors, assistant and associate professors, postdoctoral researchers, research technicians, and a large, active group of PhD candidates and physician-scientists. Rather than working in isolation, you will be embedded in a collaborative research environment where colleagues with complementary expertise work closely together and actively support one another. We have an open and informal culture with short communication lines. Weekly lab meetings, research meetings, and scientific presentations are part of daily life. Both junior and senior researchers are approachable and actively contribute to each other's projects. Qualifications and skills Qualifications and skills We are looking for someone who: Holds a Master's degree in Medicine, Biomedical Sciences, or a related life sciences discipline. Has an interest in translational biomedical research. Is analytical, accurate, and eager to learn. Enjoys working collaboratively and communicates effectively in English. Experience with genetics, bioinformatics, or laboratory research is an advantage, but motivation and curiosity are more important. Before you apply please check our conditions for employment . Terms of employment Terms of employment You will receive a temporary position for 3-4 years. The gross monthly salary amounts a minimum of € 3217,- and a maximum of € 4077,- (scale OIO). Excellent fringe benefits, such as a 13th month that is already paid out in November and a individual travel expense package. An International Office which aids you in preparing for you arrival and stay. Pension insurance with ABP. We take care of approximately 2/3 of the monthly contribution. Special benefits, such as a incompany physiotherapist and bicycle repairer. And there is also a gym where you can work on your fitness after work. More information More information Ready to make this project your next challenge? Apply now using the application button. If you would like more information about the position, please contact Dr Mahdi Salih , nephrologist, at [email protected] or +31 6 26139680 . Interested in experiencing the research environment first-hand? You are welcome to spend a day with our team before applying. Please contact Dr Mahdi Salih to arrange a visit. No agencies please. Application proces Application proces 1 Apply Step 1 - Apply Did we get you excited about this position? Submit your application through the application button. You will receive a confirmation of receipt from our recruiter right away. 2 Selection Step 2 - Selection Based on your application, we check to see if there is a fit between us. We will let you know as soon as possible whether you are invited for an interview. 3 Job interview Step 3 - Job interview You have been invited for an interview, great! In this first meeting we get to know each other and see if You can form an idea of the position, the department and Erasmus MC. If the interview goes well usually a second interview follows. 4 Offer and terms of employment Step 4 - Offer and terms of employment It’s a match! Your future manager will discuss your salary and employment with you. You will also receive more information about our other terms of employment. 5 Getting started Step 5 - Getting started Your first working day has come! We are more than happy to have you. Your new department will give you a warm welcome and provide you with all the information you need. Enjoy your job at Erasmus MC! Learn more? Renske Timmerman Recruiter +316 25679818 Contact via WhatsApp Contact Share vacancy Deel via LinkedIn Share via email Share via WhatsApp